About: Cyproterone Acetate     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz:8890 associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Cyproterone Acetate
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
  • Steroid
Preferred_Name
  • Cyproterone Acetate
NSC_Code
  • 81430
UMLS_CUI
  • C0056855
CAS_Registry
  • 427-51-0
FDA_UNII_Code
  • 4KM2BN5JHF
Contributing_Source
  • FDA
ALT_DEFINITION
  • A synthetic hormone being studied for treatment of hot flashes in men with prostate cancer who have had both testicles removed by surgery.NCI-GLOSS
PDQ_Open_Trial_Search_ID
  • 39203
PDQ_Closed_Trial_Search_ID
  • 39203
Chemical_Formula
  • C24H29ClO4
Legacy_Concept_Name
  • Cyproterone_Acetate
CHEBI_ID
  • CHEBI:50743
FULL_SYN
  • Andro-DianeFBNCI
  • Chloro-6-hydroxy-17 Alpha Methylene-1 Alpha, 2 Alpha Pregnadiene-4,6 Dione-3, 20 AcetateSNNCI
  • SH 714SYDTPNSC0081430
  • SH-714SYDTPNSC0081430
  • cyproterone acetatePTNCI-GLOSSCDR0000046077
  • Cyproterone AcetatePTDCP00422
  • CyproteronazetatSYNCI
  • CyPatABNCI
  • DianeFBNCI
  • SH-714CNNCI
  • AndrocurSYDTPNSC0081430
  • 6-Chloro-1b,2b-dihydro-17a-hydroxy-3'H-cyclopropa[1,2]pregna-1,4,6-triene-3,20-dione AcetateSNNCI
  • Cyproteroni AcetasSYNCI
  • CyproneFBNCI
  • Cyproterone AcetatePTNCI
  • DianetteFBNCI
  • AndrocurFBNCI
  • CYPROTERONE ACETATEPTFDA4KM2BN5JHF
  • 3'H-Cyclopropa(1,2)pregna-1,4,6-triene-3,20-dione, 17-(Acetyloxy)-6-chloro-1,2-dihydro-, (1beta,2beta)-SNNCI
  • CyprostatFBNCI
DEFINITION
  • The acetate salt of a synthetic steroidal antiandrogen with weak progestational and antineoplastic activities. Cyproterone binds the androgen receptor (AR), thereby preventing androgen-induced receptor activation in target tissues and inhibiting the growth of testosterone-sensitive tumor cells. This agent also exerts progestational agonist properties at the level of the pituitary that reduce luteinizing hormone (LH), resulting in reductions in testicular androgen secretion and serum testosterone levels. Treatment with cyproterone alone results in incomplete suppression of serum testosterone levels.NCI
code
  • C1059
sameAs
http://linked.open...y/mesh/hasConcept
is Has_Salt_Form of
is sameAs of
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