About: Vecuronium     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : http://linked.opendata.cz/ontology/drugbank/Drug, within Data Space : linked.opendata.cz:8890 associated with source document(s)

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rdf:type
http://linked.open...gbank/description
  • Monoquaternary homolog of pancuronium. A non-depolarizing neuromuscular blocking agent with shorter duration of action than pancuronium. Its lack of significant cardiovascular effects and lack of dependence on good kidney function for elimination as well as its short duration of action and easy reversibility provide advantages over, or alternatives to, other established neuromuscular blocking agents. [PubChem] (en)
http://linked.open...y/drugbank/dosage
http://linked.open...gy/drugbank/group
  • approved (en)
http://linked.open...drugbank/halfLife
  • 51–80 minutes (en)
http://linked.open...ugbank/indication
  • Vecuronium is a muscle relaxing agent and is used as an ajunct in general anesthesia. (en)
sameAs
Title
  • Vecuronium (en)
adms:identifier
http://linked.open...mechanismOfAction
  • Vecuronium is a bisquaternary nitrogen compound that acts by competitively binding to nicotinic cholinergic receptors. The binding of vecuronium decreases the opportunity for acetylcholine to bind to the nicotinic receptor at the postjunctional membrane of the myoneural junction. As a result, depolarization is prevented, calcium ions are not released and muscle contraction does not occur. (en)
http://linked.open...drugbank/packager
http://linked.open...outeOfElimination
  • Fecal (40-75%) and renal (30% as unchanged drug and metabolites) (en)
http://linked.open.../drugbank/synonym
  • Vecuronium (en)
  • SID50112721 (en)
http://linked.open.../drug/hasAHFSCode
http://linked.open...ynthesisReference
  • Frans Herwig Jan Jansen, "Process to prepare pharmaceutical compositions containing vecuronium bromide and compositions produced thereby." U.S. Patent US5681573, issued January, 1969. (en)
foaf:page
http://linked.open...ugbank/IUPAC-Name
http://linked.open...gy/drugbank/InChI
http://linked.open...Molecular-Formula
http://linked.open.../Molecular-Weight
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  • 50700-72-6 (en)
http://linked.open...gbank/containedIn
http://linked.open...k/Bioavailability
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http://linked.open...nk/MDDR-Like-Rule
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http://linked.open...bank/Rule-of-Five
http://linked.open...tional-IUPAC-Name
http://linked.open...-strongest-basic-
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