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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz:8890 associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Bacampicillin
rdfs:subClassOf
Has_Salt_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Bacampicillin
UMLS_CUI
  • C0052865
CAS_Registry
  • 50972-17-3
FDA_UNII_Code
  • 8GM2J22278
Contributing_Source
  • FDA
Chemical_Formula
  • C21H27N3O7S
Legacy_Concept_Name
  • Bacampicillin
CHEBI_ID
  • CHEBI:2968
FULL_SYN
  • BACAMPICILLINPTFDA8GM2J22278
  • BacampicillinPTNCI
DEFINITION
  • A prodrug of ampicillin, a broad-spectrum, semisynthetic, beta-lactam aminopenicillin antibiotic with bactericidal activity. Bacampicillin is hydrolyzed in vivo by esterases to its active metabolite ampicillin. Ampicillin binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This interrupts bacterial cell wall synthesis and results in the weakening of the bacterial cell wall and causes cell lysis.NCI
code
  • C65245
sameAs
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