About: Cephapirin     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz:8890 associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Cephapirin
rdfs:subClassOf
Has_Salt_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Cephapirin
UMLS_CUI
  • C0007737
CAS_Registry
  • 21593-23-7
FDA_UNII_Code
  • 89B59H32VN
Contributing_Source
  • FDA
Chemical_Formula
  • C17H17N3O6S2
Legacy_Concept_Name
  • Cephapirin
CHEBI_ID
  • CHEBI:554446
FULL_SYN
  • CEPHAPIRINPTFDA89B59H32VN
  • CephapirinPTNCI
DEFINITION
  • A semisynthetic, broad-spectrum, first-generation cephalosporin with antibacterial activity. Cephapirin binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.NCI
code
  • C61670
sameAs
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