About: Formoterol Fumarate     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz:8890 associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Formoterol Fumarate
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Formoterol Fumarate
NSC_Code
  • 299587
UMLS_CUI
  • C0771469
CAS_Registry
  • 43229-80-7
FDA_UNII_Code
  • P3T5QA5J9N
Contributing_Source
  • FDA
Chemical_Formula
  • 2C19H24N2O4.C4H4O4
Legacy_Concept_Name
  • Formoterol_Fumarate
CHEBI_ID
  • CHEBI:31633
FULL_SYN
  • Formamide, N-(2-hydroxy-5-((1R)-1-hydroxy-2-(((1R)-2-(4-methoxyphenyl)-1-methylethyl)amino)ethyl)phenyl)-, rel-,(E)-2-butenedioate(2:1)(salt)SNNCI
  • ForadilBRNCI
  • Formoterol FumaratePTNCI
  • FORMOTEROL FUMARATEPTFDAP3T5QA5J9N
DEFINITION
  • The fumarate salt form of formoterol, a long-acting and selective sympathomimetic beta-receptor agonist with bronchodilator activity. Formoterol fumarate binds beta 2 adrenergic receptors in bronchial smooth muscle and stimulates intracellular adenyl cyclase, thereby increasing the production of cyclic adenosine monophosphate (cAMP). Increased cAMP levels cause relaxation of bronchial smooth muscle, improve mucociliary clearance and reduce mediator substance release in inflammatory cells, especially from mast cells. (NCI05)NCI
code
  • C47540
sameAs
http://linked.open...y/mesh/hasConcept
is Has_Salt_Form of
is sameAs of
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