About: Edrophonium Chloride     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz:8890 associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Edrophonium Chloride
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Edrophonium Chloride
UMLS_CUI
  • C0013617
CAS_Registry
  • 116-38-1
FDA_UNII_Code
  • QO611KSM5P
Contributing_Source
  • FDA
Chemical_Formula
  • C10H16NO.Cl
Legacy_Concept_Name
  • Edrophonium_Chloride
CHEBI_ID
  • CHEBI:4759
FULL_SYN
  • EDROPHONIUM CHLORIDEPTFDAQO611KSM5P
  • Benzenaminium, N-ethyl-3-hydroxy-N,N-dimethyl-, ChlorideSNNCI
  • EnlonSYNCI
  • Ethyl(m-hydroxyphenyl) Dimethylammonium ChlorideSNNCI
  • AntirexSYNCI
  • TensilonSYNCI
  • ReversolSYNCI
  • Edrophonium ChloridePTNCI
DEFINITION
  • The chloride salt form of edrophonium, a short and rapid-acting cholinesterase inhibitor with parasympathomimetic activity. Echothiophate chloride potentiates the action of endogenous acetylcholine by inhibiting acetylcholinesterase that hydrolyzes acetylcholine. When applied topically to the eye, this agent prolongs stimulation of the parasympathetic receptors at the neuromuscular junctions of the longitudinal muscle of the ciliary body. Contraction of longitudinal muscle pulls on the scleral spur, and opens the trabecular meshwork, thereby increases aqueous humor outflow from the eye and reduces intraocular pressure.NCI
code
  • C47507
sameAs
http://linked.open...y/mesh/hasConcept
is Has_Salt_Form of
is sameAs of
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