About: Chloroquine Phosphate     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz:8890 associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Chloroquine Phosphate
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Chloroquine Phosphate
NSC_Code
  • 14050
UMLS_CUI
  • C0055447
CAS_Registry
  • 50-63-5
FDA_UNII_Code
  • 6E17K3343P
Contributing_Source
  • FDA
Chemical_Formula
  • C18H26ClN3.2H3O4P
Legacy_Concept_Name
  • Chloroquine_Phosphate
FULL_SYN
  • CHLOROQUINE PHOSPHATEPTFDA6E17K3343P
  • Aralen PhosphateBRNCI
  • 7-Chloro-4-((4-(diethylamino)-1-methylbutyl)amino)quinoline Phosphate (1:2)SNNCI
  • TanakanSYNCI
  • AvloclorSYNCI
  • 1,4-Pentanediamine, N4-(7-chloro-4-quinolinyl)-N1,N1-diethyl-, Phosphate (1:2)SNNCI
  • Chloroquine PhosphatePTNCI
DEFINITION
  • The phosphate salt of chloroquine, a quinoline compound with antimalarial and anti-inflammatory properties. Chloroquine is the most widely used drug against malaria, except for those cases caused by chloroquine resistant Plasmodium falciparum. Although the mechanism of action is not fully understood, chloroquine is shown to inhibit the parasitic enzyme heme polymerase that converts the toxic heme into non-toxic hemazoin, thereby resulting in the accumulation of toxic heme within the parasite. Chloroquine may also interfere with the biosynthesis of nucleic acids.NCI
code
  • C47445
sameAs
http://linked.open...y/mesh/hasConcept
is Has_Salt_Form of
is sameAs of
Faceted Search & Find service v1.16.121 as of Mar 31 2025


Alternative Linked Data Documents: ODE     Content Formats:   [cxml] [csv]     RDF   [text] [turtle] [ld+json] [rdf+json] [rdf+xml]     ODATA   [atom+xml] [odata+json]     Microdata   [microdata+json] [html]    About   
This material is Open Knowledge   W3C Semantic Web Technology [RDF Data]
OpenLink Virtuoso version 07.20.3240 as of Mar 31 2025, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 14 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2025 OpenLink Software