About: Pamidronate Disodium

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About: Pamidronate Disodium Goto Sponge NotDistinct Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz:8890 associated with source document(s)

Attributes	Values
rdf:type	Class
rdfs:label	Pamidronate Disodium
rdfs:subClassOf	Diphosphonates Bone Resorption Inhibitor
Has_Free_Acid_Or_Base_Form	PAMIDRONATE
Concept_In_Subset	FDA Established Names and Unique Ingredient Identifier Codes Terminology
Semantic_Type	Organic Chemical Pharmacologic Substance
Preferred_Name	Pamidronate Disodium
NSC_Code	720699
UMLS_CUI	C0356588
CAS_Registry	109552-15-0
Accepted_Therapeutic_Use_For	Hypercalcemia of malignancy; Osteolytic bone lesions of multiple myeloma; Osteolytic bone metastases of breast cancer; Pagets disease
In_Clinical_Trial_For	Multiple myeloma; Osteogenesis imperfecta
FDA_UNII_Code	8742T8ZQZA
Contributing_Source	FDA
PDQ_Open_Trial_Search_ID	39149
PDQ_Closed_Trial_Search_ID	39149
Chemical_Formula	C3H9NO7P2.2Na.5H2O
Legacy_Concept_Name	Pamidronate_Disodium
FULL_SYN	PAMIDRONATE DISODIUMPTFDA8742T8ZQZA ArediaBRNCI AminomuxFBNCI Pamidronate DisodiumPTNCI GCP-23339ACNNCI
DEFINITION	The disodium salt of the synthetic bisphosphonate pamidronate. Although its mechanism of action is not completely understood, pamidronate appears to adsorb to calcium phosphate crystals in bone, blocking their dissolution by inhibiting osteoclast-mediated bone resorption. This agent does not inhibit bone mineralization and formation.NCI
code	C1345
sameAs	PAMIDRONATE DISODIUM
http://linked.open...y/mesh/hasConcept	http://linked.opendata.cz/resource/mesh/concept/M0313839
is someValuesFrom of	nodeID://b660057
is Has_Salt_Form of	PAMIDRONATE
is sameAs of	PAMIDRONATE DISODIUM PAMIDRONATE DISODIUM

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