About: INDO wt Allele     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz:8890 associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • INDO wt Allele
rdfs:subClassOf
OMIM_Number
  • 147435
GenBank_Accession_Number
  • M34455
Semantic_Type
  • Gene or Genome
Preferred_Name
  • INDO wt Allele
UMLS_CUI
  • C2697654
EntrezGene_ID
  • 3620
Legacy_Concept_Name
  • INDO_wt_Allele
HGNC_ID
  • HGNC:6059
FULL_SYN
  • Indoleamine-Pyrrole 2,3 Dioxygenase wt AlleleSYNCI
  • INDO wt AllelePTNCI
  • IDOSYNCI
  • IDO1SYNCI
  • CD107BSYNCI
DEFINITION
  • Human INDO wild-type allele is located within 8p12-p11 and is approximately 15 kb in length. This allele, which encodes indoleamine 2,3-dioxygenase protein, plays a role in tryptophan metabolism. Expression of the gene is associated with reduction in cellular immune responses.NCI
DesignNote
  • Aberrant expression of the INDO gene by tumor cells may be associated with resistance to cell-mediated immunity.
code
  • C79780
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