About: Cefovecin Sodium     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz:8890 associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Cefovecin Sodium
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Cefovecin Sodium
UMLS_CUI
  • C2699141
CAS_Registry
  • 141195-77-9
FDA_UNII_Code
  • DL8Q24959P
Contributing_Source
  • FDA
Chemical_Formula
  • C17H18N5O6S2.Na
Legacy_Concept_Name
  • Cefovecin_Sodium
FULL_SYN
  • CEFOVECIN SODIUMPTFDADL8Q24959P
  • Cefovecin SodiumPTNCI
DEFINITION
  • The sodium salt form of cefovecin, a semisynthetic, broad-spectrum, third-generation cephalosporin with antibacterial activity. Cefovecin binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.NCI
code
  • C76036
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