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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz:8890 associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Difenoxin
rdfs:subClassOf
Has_Salt_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Difenoxin
UMLS_CUI
  • C0057981
CAS_Registry
  • 28782-42-5
FDA_UNII_Code
  • 3ZZ5BJ9F2Q
Contributing_Source
  • FDA
Chemical_Formula
  • C28H28N2O2
Legacy_Concept_Name
  • Difenoxin
CHEBI_ID
  • CHEBI:4534
FULL_SYN
  • McN-JR 15,403-11CNNCI
  • 1-(3-Cyano-3,3-diphenylpropyl)-4-phenylisonipecotic AcidSNNCI
  • DIFENOXINPTFDA3ZZ5BJ9F2Q
  • DifenoxinPTNCI
DEFINITION
  • A phenylpiperidine with antidiarrheal activity and an active metabolite of diphenoxylate. Difenoxin is chemically related to the narcotic opioid meperidine. Difenoxin acts primarily on the gastrointestinal wall by binding to opioid receptors on acetylcholine-containing nerves and inhibiting the release of acetylcholine from presynaptic nerve terminals. This leads to a reduction in intestinal motility. Difenoxin hydrochloride also mimics the action of endogenous opioid peptides at the CNS opioid receptors, (primarily mu-receptors), thereby inducing CNS effects.NCI
code
  • C65381
sameAs
http://linked.open...y/mesh/hasConcept
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