About: Felodipine     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz:8890 associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Felodipine
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Felodipine
UMLS_CUI
  • C0015772
CAS_Registry
  • 72509-76-3
FDA_UNII_Code
  • OL961R6O2C
Contributing_Source
  • FDA
Chemical_Formula
  • C18H19Cl2NO4
Legacy_Concept_Name
  • Felodipine
CHEBI_ID
  • CHEBI:585948
FULL_SYN
  • FelodipinePTDCP01010
  • PlendilBRNCI
  • FELODIPINEPTFDAOL961R6O2C
  • FelodipinePTNCI
DEFINITION
  • A dihydropyridine calcium channel blocking agent. Felodipine inhibits the influx of extracellular calcium ions into myocardial and vascular smooth muscle cells, causing dilatation of the main coronary and systemic arteries and decreasing myocardial contractility. This agent also inhibits the drug efflux pump P-glycoprotein which is overexpressed in some multi-drug resistant tumors and may improve the efficacy of some antineoplastic agents. (NCI04)NCI
code
  • C29046
sameAs
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