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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz:8890 associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Cefaclor
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Antibiotic
  • Organic Chemical
Preferred_Name
  • Cefaclor
UMLS_CUI
  • C0007537
CAS_Registry
  • 70356-03-5
FDA_UNII_Code
  • 69K7K19H4L
Contributing_Source
  • FDA
Chemical_Formula
  • C15H14ClN3O4S.H2O
Legacy_Concept_Name
  • Cefaclor
FULL_SYN
  • CEFACLORPTFDA69K7K19H4L
  • Cefaclor HydrateSYNCI
  • CefaclorPTNCI
DEFINITION
  • A beta-lactam, second-generation cephalosporin antibiotic with bactericidal activity. Cefaclor binds to and inactivates penicillin-binding proteins (PBP) located in bacterial cytoplasmic membranes. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.NCI
code
  • C28911
sameAs
http://linked.open...y/mesh/hasConcept
is sameAs of
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