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| Description
| - The aim of the project is to compare the properties of the main enzymes of biotransformation of foreign compounds in pig and in the man, namely, cytochromes P450 and uridindiphosphoglucuronosyltransferases (UGT). Activities of these enzymes of the pig and human origin will be compared using model substrates. (en)
- Cílem projektu je získat informace o podobnosti lidských a prasečích jaterních enzymů účastnících se biotransformace (metabolismu) cizorodých látek. Cíle bude dosaženo srovnáním aktivit CYP (CYP2E1 a CYP2A19 resp. CYP2A6) a mikrosomálních UGT a SULT.
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| Title
| - Porcine enzymes of biotransformation (en)
- Porcinní biotransformační enzymy
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| skos:notation
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| http://linked.open...avai/cep/aktivita
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| http://linked.open...kovaStatniPodpora
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| http://linked.open...ep/celkoveNaklady
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| http://linked.open...datumDodatniDoRIV
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| http://linked.open...i/cep/druhSouteze
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| http://linked.open...ep/duvernostUdaju
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| http://linked.open.../cep/fazeProjektu
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| http://linked.open...ai/cep/hlavniObor
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| http://linked.open...hodnoceniProjektu
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| http://linked.open...vai/cep/kategorie
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| http://linked.open.../cep/klicovaSlova
| - Cytochromes P450; CYP; glucuronidation; sulfation; UDPGT; UGT; SULT; pig (en)
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| http://linked.open...ep/partnetrHlavni
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| http://linked.open...inujicichPrijemcu
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| http://linked.open...cep/pocetPrijemcu
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| http://linked.open...ocetSpoluPrijemcu
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| http://linked.open.../pocetVysledkuRIV
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| http://linked.open...enychVysledkuVRIV
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| http://linked.open...lneniVMinulemRoce
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| http://linked.open.../prideleniPodpory
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| http://linked.open...iciPoslednihoRoku
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| http://linked.open...atUdajeProjZameru
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| http://linked.open.../vavai/cep/soutez
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| http://linked.open...usZobrazovaneFaze
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| http://linked.open...ai/cep/typPojektu
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| http://linked.open...ep/ukonceniReseni
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| http://linked.open.../cep/vedlejsiObor
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| http://linked.open...ep/zahajeniReseni
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| http://linked.open...jektu+dodavatelem
| - 1. Matal J, Tunková A, Šiller M, Anzenbacherová E, Anzenbacher P Isolation of two cytocchrome P450 forms, CYP2A19 and CYP1A, from pig liver microsemes. J Vet Pharmacol Ther. 32(5): 470 - 476. 2. Matal J, Matušková Z, Tunková A, Anzanbacher P Porcine CYP2A19, 2E1 and 1A2 froms are responsible for skatole biotransformation in the reconstituted system. (en)
- 1. Matal J, Tunková A, Šiller M, Anzenbacherová E, Anzenbacher P Isolation of two cytocchrome P450 forms, CYP2A19 and CYP1A, from pig liver microsemes. J Vet Pharmacol Ther. 32(5): 470 - 476. 2. Matal J, Matušková Z, Tunková A, Anzanbacher P Porcine CYP2A19, 2E1 and 1A2 froms are responsible for skatole biotransformation in the reconstituted system. (cs)
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| http://linked.open...tniCyklusProjektu
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| http://linked.open.../cep/klicoveSlovo
| - Cytochromes P450
- CYP
- SULT
- UDPGT
- UGT
- glucuronidation
- sulfation
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| is http://linked.open...vavai/cep/projekt
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