About: The influence of TSPY gene sequence, repetition and expression variability on biological function in normal and pathological cells.     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Projekt, within Data Space : linked.opendata.cz:8890 associated with source document(s)

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Description
  • The project is mainly aimed on testing of correlation between varieties of TSPY genes and germinal tumor and gonadoblastoma development. Also study the influence of types of the TSPY genes on spermatogenesis. (en)
  • Projekt je zaměřen především na testování korelace mezi zastoupením variant TSPY genů a rozvojem germinálního tumoru a gonadoblastomu a na vliv variant genů TSPY na spermatogenezi.
Title
  • The influence of TSPY gene sequence, repetition and expression variability on biological function in normal and pathological cells. (en)
  • Vliv sekvenční, repetiční a expresní variability genu TSPY na biologickou funkci v normálních a patologických buňkách.
skos:notation
  • NR7821
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  • TSPY; testicular tumor; gonadoblastoma; spermatogenesis; tumorogenesis; chromosome Y (en)
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  • Autoři vypracovali metody na vyšetření polymorfir ( repetice a sekvenční variability) genu TSPY (testisspecific protein) lokalizovaného na Y chromosomu. Prokázali význam těchto metod pro odhalení neplodnsoti mužů a rozpoznání maligní a zdravé tkáně. (cs)
  • Authors elaborated methods for investigation of repetion and sequential variability of TSP-Y encoded gene. They demostrated the significance of these methods for detection of male infertibility and recognition of malignant and healthy tissuue. (en)
http://linked.open...tniCyklusProjektu
http://linked.open.../cep/klicoveSlovo
  • TSPY
  • gonadoblastoma
  • spermatogenesis
  • testicular tumor
  • tumorogenesis
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