About: The importance of mammaglobin and cytokeratin 19 detection in axillary lymph nodes,bone marrow and peripheral blood in the assesment of minimal residual disease in human breast cancer patients     Goto   Sponge   NotDistinct   Permalink

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Description
  • From patients with human breast carcinoma will be taken the specimen of peripheral blood and bone marrow aspirates at the time of diagnosis. We will also prepare for the examination specimens from removed axillary lymph nodes. All these specimens will be examined for the overexpression of mammaglobin. The method used will be RT PCR. Bone marrow aspirates and peripheral blood will be examined at the latest six month after diagnosis by the same method. The same examination will be performed at the time of possible recurrence. (en)
  • u pacientek s karcinomem prsu bude v době diagnózy odebrán vzorek krve a kostní dřeně. Spolu s pooperačním vzorkem axilárních uzlin budou vyšetřeny pomocí metody RT PCR na zvýšenou expresy mammaglobinu. Kostní dřeň a periferní krev bude vyšetřena po skončení adjuvantní terapie nebo nejpozději 6 měsíců po zahájení léčby stejnou metodou, stejné vyšetření bude provedeno v čase případné recidivy.
Title
  • The importance of mammaglobin and cytokeratin 19 detection in axillary lymph nodes,bone marrow and peripheral blood in the assesment of minimal residual disease in human breast cancer patients (en)
  • Význam detekce mammaglobinu a cytokeratinu 19 v lymfatických uzlinách, kostní dřeni a vzorcích periferní krve při stanovení minimální reziduální choroby u pacientek s karcinomem prsu
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  • NC6672
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  • minimal residual disease;mammaglobin;cytokeratin 19;breast carcinoma;survival;disease free interval;marker (en)
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  • Potenciální nová diagnostická metoda. (cs)
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  • survival
  • breast carcinoma
  • minimal residual disease
  • mammaglobin
  • disease free interval
  • cytokeratin 19
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