About: S-nitrosoglutathione reductase: key regulatory enzyme of the metabolism of reactive nitrogen species in plant development and stress responses     Goto   Sponge   NotDistinct   Permalink

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  • S-nitrosylation has emerged as a crucial redox-based reversible signaling mechanism in plant response to pathogenic challenge. The goal is to perform analysis of temporal and spatial modulation of S-nitrosothiols levels and expression of their catabolic enzymes as S-nitrosoglutathione reductase (GSNOR) during pathogenic infection in the cells and tissues of plants and pathogens. By a combination of biochemical, pharmacological and genetic approaches we will test the hypothesis on the relationship of S-nitrosothiol level and S-nitrosoglutathione reductase activity and plant resistance, as well as the role of S-nitrosothiols, protein S-nitrosylation and nitrosative stress in plant hypersensitive reaction and systemic response. Research will be performed on model systems including plants of high agronomical importance like tomato, lettuce and cucumber, and their relevant pathogens downy and powdery mildews. The obtained knowledge will be potentially applicable for plant genetic manipulation and breeding (en)
  • Hlavním cílem projektu je detailní poznání úlohy S-nitrosylace, S-nitrosothiolů a S-nitrosoglutathionreduktasy v rostlinné odpovědi na stresové podněty a ve vývoji pathogenů pro šlechtění a transformaci rostlin se zvýšenou odolnost na stresové podmínky.
Title
  • S-nitrosoglutathione reductase: key regulatory enzyme of the metabolism of reactive nitrogen species in plant development and stress responses (en)
  • S-nitrosoglutathionreduktasa: klíčový enzym regulace metabolismu oxidu dusnatého v rostlinách a jeho funkce v odpovědi rostlin na stresové podmínky
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  • nitric oxide reactive nitrogen species S-nitrosylation S-nitrosothiols S-nitrosoglutathione reductase nitrosative stress plant defense responses biotic stress abiotic stress (en)
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