About: The influence of gene variability on the bioavailability of immunosuppressiv drugs and its relation to the short-term and long-term outcome of kidney transplantation     Goto   Sponge   NotDistinct   Permalink

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  • Observation of the influence of polymorphisms in CYP3A4, CYP3A5 and MDR-1 genes on the metabolism of immunosuppressive drugs in kidney transplant recipients. Observation of effect of polymorphisms in CYP3A4, CYP3A5 and MDR-1 genes on the occurrence of early acute rejection and long-term complications after kidney transplantation. (en)
  • Sledování vlivu polymorfismu genů pro CYP3A4, CYP3A5 a MDR-1 na metabolismus a vstřebávání imunosupresiv a jejich souvislost s úspěšností imunosupresivní léčby. Sledování vlivu polymorfismu genů pro CYP3A4, CYP3A5 a MDR-1 na vznik časné akutní rejekce a dlouhodobé komplikace po transplantaci ledviny. (cs)
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  • The influence of gene variability on the bioavailability of immunosuppressiv drugs and its relation to the short-term and long-term outcome of kidney transplantation (en)
  • Variabilita genů ovlivňující biologickou dostupnost imunosupresiv a její vztah ke krátkodobým i dlouhodobým výsledkům transplantace ledviny (cs)
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  • kidney transplantation; immunosuppressive drugs; gene polymorphism; pharmacogenetics; cyclosporine; tacrolimus (en)
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