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  • Vyvinutí a ověření nové metody stanovení cirkulujících hladin endogenních hydroxylovaných metabolitů vitaminu D pomocí imunochemických a chromatografických technik s UV nebo fluorescenční detekcí nativních nebo derivatizovaných analytů. Stanovení cirkulujících hydroxylovaných metabolitů vitaminu D u dětí trpících závažnou ledvinnou nedostatečností a u pacientů s poruchou remodelace kosti. (cs)
  • Developing and validation of method for determination of circulating endogenous vitamin D hydroxylated metabolites using immunochemical and chromatographic techniques with UV or fluorimetric detection of native or derivatized analytes. Determination of circulating vitamin D hydroxylated metabolites in children with serious renal failure (200 sample per year) and in patients with defective bone remodeling (200 samples). (en)
Title
  • Vývoj nových metodik stanovení metabolitů vitamínu D v biologickém materiálu. (cs)
  • Development of new methods for determination of vitamin D metabolites in biological material. (en)
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  • vitamin D; metabolites; chromatography; immunoassay; derivatization; determination (en)
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