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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz:8890 associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Lisinopril Anhydrous
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Lisinopril Anhydrous
UMLS_CUI
  • C2827257
CAS_Registry
  • 76547-98-3
FDA_UNII_Code
  • 7Q3P4BS2FD
Contributing_Source
  • FDA
Chemical_Formula
  • C21H31N3O5
CHEBI_ID
  • CHEBI:43755
FULL_SYN
  • LISINOPRIL ANHYDROUSPTFDA7Q3P4BS2FD
  • L-Proline, 1-(N(Sup 2)-(1-Carboxy-3-Phenylpropyl)-L-Lysyl)-SNNCI
  • 1-(N(Sup 2)-((S)-1-Carboxy-3-Phenylpropyl)-L-Lysyl)-L-ProlineSNNCI
  • Lisinopril AnhydrousPTNCI
DEFINITION
  • The anhydrous form of the long-acting angiotensin-converting enzyme (ACE) inhibitor lisinopril with antihypertensive activity. Lisinopril, a synthetic peptide derivative, competitively binds to and inhibits ACE, thereby blocking the conversion of angiotensin I to angiotensin II. This prevents the potent vasoconstrictive actions of angiotensin II and results in vasodilation. Lisinopril also decreases angiotensin II-induced aldosterone secretion by the adrenal cortex, which leads to an increase in sodium excretion and subsequently increases water outflow.NCI
code
  • C83924
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