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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz:8890 associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Peptichemio
rdfs:subClassOf
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Pharmacologic Substance
Preferred_Name
  • Peptichemio
UMLS_CUI
  • C0030927
CAS_Registry
  • 9076-25-9
ALT_DEFINITION
  • A mixture of six synthetic oligopeptides, each containing MELPHALAN. It is used as a broad-spectrum antineoplastic due to its alkylating and antimetabolic actions but, is toxic to bone marrow, gastrointestinal system and vasculature.MSH2002_06_01
PDQ_Open_Trial_Search_ID
  • 39541
PDQ_Closed_Trial_Search_ID
  • 39541
Legacy_Concept_Name
  • Peptichemio
FULL_SYN
  • PTCSYNCI
  • PeptichemioPTNCI
  • peptide bound m-L-sarcolysinSYNCI
  • MultialchilpeptideSYNCI
DEFINITION
  • A mixture of six synthetic oligopeptides in which the peptides are conjugated to metamelphalan, with alkylating and potential antineoplastic activity. Peptichemio causes crosslinking of DNA, thereby preventing DNA replication and eventually cellular proliferation.NCI
code
  • C734
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