About: Protokylol Hydrochloride     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz:8890 associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Protokylol Hydrochloride
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Protokylol Hydrochloride
UMLS_CUI
  • C0770472
CAS_Registry
  • 136-69-6
FDA_UNII_Code
  • 7U7O8Q48IO
Contributing_Source
  • FDA
Chemical_Formula
  • C18H21NO5.HCl
Legacy_Concept_Name
  • Protokylol_Hydrochloride
FULL_SYN
  • Protokylol HydrochloridePTNCI
  • PROTOKYLOL HYDROCHLORIDEPTFDA7U7O8Q48IO
DEFINITION
  • The hydrochloride salt form of protokylol, a derivative of the beta-adrenergic receptor agonist isoproterenol with bronchodilator activity. Protokylol binds to beta-2 adrenergic receptors in bronchial smooth muscle, thereby activating intracellular adenyl cyclase, an enzyme that catalyzes the conversion of adenosine triphosphate (ATP) to cyclic-3',5'-adenosine monophosphate (cAMP). Increased cAMP levels cause relaxation of bronchial smooth muscle, relieve bronchospasms, improve mucociliary clearance and inhibit the release of mediators of immediate hypersensitivity from cells, especially from mast cells.NCI
code
  • C66496
is Has_Salt_Form of
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