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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz:8890 associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Dioxifedrine
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Dioxifedrine
UMLS_CUI
  • C1880341
CAS_Registry
  • 10329-60-9
FDA_UNII_Code
  • CF48QOH154
Contributing_Source
  • FDA
Chemical_Formula
  • C10H15NO3
Legacy_Concept_Name
  • Dioxifedrine
FULL_SYN
  • DIOXIFEDRINEPTFDACF48QOH154
  • DioxifedrinePTNCI
DEFINITION
  • A beta-2 -adrenergic agonist with bronchodilator activity. Dioxifedrine selectively binds to and activates beta-2 adrenergic receptors in bronchiolar smooth muscle, thereby causing stimulation of adenyl cyclase, the enzyme that catalyzes the conversion of adenosine triphosphate (ATP) to cyclic-3',5'-adenosine monophosphate (cAMP). Increased intracellular cAMP levels cause relaxation of bronchial smooth muscle. This increases air flow and prevents bronchospasms and may eventually lead to an improvement of airway function.NCI
code
  • C65417
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