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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz:8890 associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Alfuzosin
rdfs:subClassOf
Has_Salt_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Alfuzosin
UMLS_CUI
  • C0051150
CAS_Registry
  • 81403-80-7
FDA_UNII_Code
  • 90347YTW5F
Contributing_Source
  • FDA
Chemical_Formula
  • C19H27N5O4
Legacy_Concept_Name
  • Alfuzosin
CHEBI_ID
  • CHEBI:51141
FULL_SYN
  • ALFUZOSINPTFDA90347YTW5F
  • (+/-)-N-(3-((4-amino-6,7-dimethoxyquinazolin-2-yl)(methyl)amino)propyl)tetrahydrofuran-2-carboxamideSNNCI
  • N-(3-((4-Amino-6,7-dimethoxy-2-quinazolinyl)methylamino)propyl)tetrahydro-2-furancarboxamideSNNCI
  • AlfuzosinPTNCI
DEFINITION
  • A synthetic quinazoline compound with smooth muscle relaxing activity. Alfuzosin selectively binds to and antagonizes alpha-1-adrenergic receptors in smooth muscle of the bladder neck and prostate, thereby relaxing the smooth muscle and decreasing the obstruction and urethral resistance seen with benign prostate hyperplasia (BPH) and prostate cancer. This agent also blocks alpha-1-adrenergic receptors in peripheral vascular smooth muscle, which leads to vasodilatation and a subsequent decrease in peripheral vascular resistance.NCI
code
  • C61627
is Has_Free_Acid_Or_Base_Form of
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