About: Fluphenazine Hydrochloride     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz:8890 associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Fluphenazine Hydrochloride
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Fluphenazine Hydrochloride
NSC_Code
  • 179197
UMLS_CUI
  • C0700567
CAS_Registry
  • 146-56-5
FDA_UNII_Code
  • ZOU145W1XL
Contributing_Source
  • FDA
ALT_DEFINITION
  • A drug that is used to treat mental and emotional disorders and is being studied in the treatment of multiple myeloma. Fluphenazine hydrochloride may stop tumor growth by keeping myeloma cells from dividing and causing them to die. It is a type of antipsychotic.NCI-GLOSS
PDQ_Open_Trial_Search_ID
  • 487523
PDQ_Closed_Trial_Search_ID
  • 487523
Chemical_Formula
  • C22H26F3N3OS.2HCl
Legacy_Concept_Name
  • Fluphenazine_Hydrochloride
FULL_SYN
  • Fluphenazine HydrochloridePTNCI
  • fluphenazine hydrochloridePTNCI-GLOSSCDR0000535480
  • FLUPHENAZINE HYDROCHLORIDEPTFDAZOU145W1XL
  • PermitilBRNCI
  • ProlixinBRNCI
DEFINITION
  • The hydrochloride salt of fluphenazine, a phenothiazine with antipsychotic activity and potential antineoplastic activity. Fluphenazine blocks postsynaptic dopamine D2 receptors in the limbic system, cortical system and basal ganglia, resulting in a reduction of schizophrenia-associated hallucinations and delusions. In addition, as a serotonin antagonist, this agent may inhibit lymphocyte and myeloma cell proliferation by blocking 5-hydroxytrptamine type 1B (5-HT type 1B) receptors for serotonin.NCI
code
  • C47995
is Has_Salt_Form of
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