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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz:8890 associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Pirbuterol Acetate
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Pirbuterol Acetate
UMLS_CUI
  • C0724666
CAS_Registry
  • 65652-44-0
FDA_UNII_Code
  • 1EH73XKR9N
Contributing_Source
  • FDA
Chemical_Formula
  • C12H20N2O3.C2H4O2
Legacy_Concept_Name
  • Pirbuterol_Acetate
FULL_SYN
  • alpha(sup 6)-((tert-Butylamino)methyl)-3-hydroxy-2,6-pyridinedimethanol Monoacetate(salt)SNNCI
  • MaxairBRNCI
  • Pirbuterol AcetatePTNCI
  • PIRBUTEROL ACETATEPTFDA1EH73XKR9N
DEFINITION
  • The acetate salt form of pirbuterol, a synthetic catecholamine and a pyridine derivative with sympathomimetic and bronchodilatory effects. Pirbuterol acetate selectively stimulates beta-2 adrenergic receptors, resulting in initiation of intracellular adenylate cyclase activity leading to increased levels of cAMP. As a result muscle relaxation (broncho- and vasodilation) occurs via cAMP-dependent signal transduction. In addition, elevated levels of cAMP inhibit release of inflammatory mediators from mast cells.NCI
code
  • C47675
is Has_Salt_Form of
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