About: Terazosin Hydrochloride     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz:8890 associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Terazosin Hydrochloride
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Organic Chemical
  • Pharmacologic Substance
Preferred_Name
  • Terazosin Hydrochloride
UMLS_CUI
  • C0591628
CAS_Registry
  • 70024-40-7
FDA_UNII_Code
  • D32S14F082
Contributing_Source
  • FDA
ALT_DEFINITION
  • A drug used to treat urinary problems caused by an enlarged prostate. It is also used to treat high blood pressure and is being studied in the treatment of other conditions. Terazosin hydrochloride relaxes muscle tissue in blood vessels and in the prostate. It is a type of alpha blocker.NCI-GLOSS
Chemical_Formula
  • C19H25N5O4.HCl.2H2O
Legacy_Concept_Name
  • Terazosin_Hydrochloride
CHEBI_ID
  • CHEBI:9446
FULL_SYN
  • terazosin hydrochloridePTNCI-GLOSSCDR0000562654
  • Terazosin Hydrochloride DihydrateSYNCI
  • Terazosin HydrochloridePTNCI
  • TERAZOSIN HYDROCHLORIDEPTFDAD32S14F082
  • HytrinPTNCI-GLOSSCDR0000562655
  • HytrinBRNCI
  • Terazosin HydrochloridePTDCP32048
DEFINITION
  • The hydrochloride salt form of terazosin, a quinazoline derivative with adrenergic antagonistic property. Terazosin hydrochloride selectively inhibits alpha-1 adrenergic receptors, resulting in vasodilation leading to decreased peripheral vascular resistance and a reduced venous return to the heart as well as decreased urethral resistance, which potentially improving urine flow and symptoms related to benign prostatic hyperplasia. In addition, terazosin decreases low-density lipoproteins (LDL) and triglycerides while increasing the concentration of high-density lipoproteins (HDL).NCI
code
  • C29491
is Has_Salt_Form of
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