About: Milrinone Lactate     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz:8890 associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Milrinone Lactate
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Organic Chemical
  • Pharmacologic Substance
Preferred_Name
  • Milrinone Lactate
UMLS_CUI
  • C0699132
CAS_Registry
  • 100286-97-3
FDA_UNII_Code
  • 9K8XR81MO8
Contributing_Source
  • FDA
Chemical_Formula
  • C12H9N3O.C3H6O3
Legacy_Concept_Name
  • Milrinone_Lactate
CHEBI_ID
  • CHEBI:34850
FULL_SYN
  • Milrinone LactatePTDCP32082
  • Milrinone LactatePTNCI
  • MILRINONE LACTATEPTFDA9K8XR81MO8
  • PrimacorBRNCI
DEFINITION
  • A bipyridine agent with positive inotropic and vasodilator properties. Milrinone lactate selectively inhibits fraction III cyclic adenosine monophosphate (cAMP) phosphodiesterase isozymes in the heart and vascular muscles, thereby increasing cAMP and, consequently, an increase in cAMP-dependent intracellular ionized calcium and myocardium contractile force, and vasodilation in arteriolar and venous vascular smooth muscle. This agent improves hemodynamics in patients with ventricular dysfunction by increasing the stroke volume index and left ventricular contractility and by producing pulmonary vasodilation. (NCI04)NCI
code
  • C29263
is Has_Salt_Form of
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