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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz:8890 associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Tacedinaline
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Organic Chemical
  • Pharmacologic Substance
Preferred_Name
  • Tacedinaline
PubMedID_Primary_Reference
  • 18497959
UMLS_CUI
  • C0217598
CAS_Registry
  • 112522-64-2
In_Clinical_Trial_For
  • Melanoma; Non-Small Cell Lung Cancer
FDA_UNII_Code
  • UMF554N5FG
Contributing_Source
  • FDA
ALT_DEFINITION
  • A substance being studied in the treatment of non-small cell lung cancer.NCI-GLOSS
PDQ_Open_Trial_Search_ID
  • 37825
PDQ_Closed_Trial_Search_ID
  • 37825
Chemical_Formula
  • C15H15N3O2
Legacy_Concept_Name
  • Acetyldinaline
FULL_SYN
  • TacedinalinePTNCI
  • AcetyldinalineSYNCI
  • CI-994PTNCI-GLOSSCDR0000044879
  • N-acetyldinalineSNNCI
  • 4-(Acetylamino)-N-(2-aminophenyl)benzamidePTDCP50123
  • N-acetyl DinalineSNNCI
  • CI-994CNNCI
  • GOE5549CNNCI
  • PD 123654CNNCI
  • N-acetyldinalinePTNCI-GLOSSCDR0000044383
  • 4-(Acetylamino)-N-(2-aminophenyl)benzamideSNNCI
  • TACEDINALINEPTFDAUMF554N5FG
DEFINITION
  • An orally bioavailable substituted benzamide derivative with potential antineoplastic activity. Tacedinaline inhibits histone deacetylation, which may result in histone hyperacetylation, followed by the induction of differentiation, the inhibition of cell proliferation, and apoptosis in susceptible tumor cell populations.NCI
code
  • C2202
is someValuesFrom of
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