About: Upstream Stimulatory Factor     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz:8890 associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Upstream Stimulatory Factor
rdfs:subClassOf
Semantic_Type
  • Amino Acid, Peptide, or Protein
Preferred_Name
  • Upstream Stimulatory Factor
UMLS_CUI
  • C0076925
Legacy_Concept_Name
  • Upstream_Stimulatory_Factor
FULL_SYN
  • USFSYNCI
  • Upstream Stimulatory FactorPTNCI
  • Upstream Transcription FactorSYNCI
DEFINITION
  • The upstream stimulatory factor is a ubiquitously expressed cellular transcription factor that binds to a symmetrical DNA sequence that is found in a variety of viral and cellular promoters. Purified USF consists of 2 related polypeptides of 43 and 44 kD encoded by USF1 and USF2, respectively. USF is known to be involved in the regulation of many gene with direct and indirect roles in cancer. (from OMIM and NCI)NCI
code
  • C17679
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