About: Perfosfamide     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz:8890 associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Perfosfamide
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
  • Organophosphorus Compound
Preferred_Name
  • Perfosfamide
NSC_Code
  • 181815
UMLS_CUI
  • C0163054
CAS_Registry
  • 39800-16-3
Accepted_Therapeutic_Use_For
  • Ex-vivo treatment of autologous bone marrow and subsequent reinfusion in patients with acute myelogenous leukemia
In_Clinical_Trial_For
  • Hodgkins lymphoma; multiple myeloma; neuroblastoma; non-Hodgkins lymphoma
FDA_UNII_Code
  • U880A4FUDA
Contributing_Source
  • FDA
PDQ_Open_Trial_Search_ID
  • 40474
PDQ_Closed_Trial_Search_ID
  • 40474
Chemical_Formula
  • C7H15Cl2N2O4P
Legacy_Concept_Name
  • Perfosfamide
CHEBI_ID
  • CHEBI:196991
FULL_SYN
  • cis-4-hydroperoxycyclophosphamideSNNCI
  • PerfosfamidePTNCI
  • 4-HCSNNCI
  • HydroperoxycyclophosphamideSYNCI
  • 4-HydroperoxycyclophosphamideSYDTPNSC0181815
  • 4-HydroperoxycyclophosphamideSNNCI
  • PergamidBRNCI
  • 4'-HydroperoxycyclophosphamideSNNCI
  • 4-HydroperoxycyclophosphamidePTDCP30297
  • 2-[bis(2-chloroethyl)amino]-4-hydroperoxytetrahydro-2H-1,3,2-oxazaphosphorine 2-oxideSNNCI
  • cis-2-[bis(2-chloroethyl)amino]tetrahydro-3H-1,3,2-oxazaphosphorin-4-yl hydroperoxide P-oxideSNNCI
  • 4-PergamidSNNCI
  • PERFOSFAMIDEPTFDAU880A4FUDA
DEFINITION
  • The active metabolite of the nitrogen mustard cyclophosphamide with potent antineoplastic and immunosuppressive properties. Perfosfamide alkylates DNA, thereby inhibiting DNA replication and RNA and protein synthesis. (NCI04)NCI
code
  • C1423
Faceted Search & Find service v1.16.121 as of Mar 31 2025


Alternative Linked Data Documents: ODE     Content Formats:   [cxml] [csv]     RDF   [text] [turtle] [ld+json] [rdf+json] [rdf+xml]     ODATA   [atom+xml] [odata+json]     Microdata   [microdata+json] [html]    About   
This material is Open Knowledge   W3C Semantic Web Technology [RDF Data]
OpenLink Virtuoso version 07.20.3240 as of Mar 31 2025, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 14 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2025 OpenLink Software