About: Ramosetron Hydrochloride

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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz:8890 associated with source document(s)

Attributes	Values
rdf:type	Class
rdfs:label	Ramosetron Hydrochloride
rdfs:subClassOf	5-HT3 Receptor Antagonist
Has_Free_Acid_Or_Base_Form	Ramosetron
Concept_In_Subset	FDA Established Names and Unique Ingredient Identifier Codes Terminology
Semantic_Type	Pharmacologic Substance
Preferred_Name	Ramosetron Hydrochloride
UMLS_CUI	C0526951
CAS_Registry	132907-72-3
FDA_UNII_Code	9551LHD87E
Contributing_Source	FDA
PDQ_Open_Trial_Search_ID	658906
PDQ_Closed_Trial_Search_ID	658906
Chemical_Formula	C17H17N3O.ClH
FULL_SYN	Ramosetron HydrochloridePTNCI RAMOSETRON HYDROCHLORIDEPTFDA9551LHD87E NaseaBRNCI YM-060CNNCI (R)-5-((1-Methyl-3-indolyl)carbonyl)-4,5,6,7-tetrahydro-1H-benzimidazole HydrochlorideSNNCI
DEFINITION	The hydrochloride salt of ramosetron, a selective serotonin (5-HT) receptor antagonist with potential antiemetic activity. Upon administration, ramosetron selectively binds to and blocks the activity of 5-HT subtype 3 (5-HT3) receptors located in the vagus nerve terminal and in the vomiting center in the central nervous system (CNS), suppressing chemotherapy-induced nausea and vomiting.NCI
code	C88299
http://linked.open...y/mesh/hasConcept	http://linked.opendata.cz/resource/mesh/concept/M0193792
is Has_Salt_Form of	Ramosetron

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