About: Ceftobiprole Medocaril     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz:8890 associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Ceftobiprole Medocaril
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Ceftobiprole Medocaril
UMLS_CUI
  • C1622308
CAS_Registry
  • 252188-71-9
FDA_UNII_Code
  • N99027V28J
Contributing_Source
  • FDA
PDQ_Open_Trial_Search_ID
  • 570771
PDQ_Closed_Trial_Search_ID
  • 570771
Chemical_Formula
  • C26H25N8O11S2.Na
Legacy_Concept_Name
  • Ceftobiprole_Medocaril
FULL_SYN
  • Ceftobiprole MedocarilPTNCI
  • CEFTOBIPROLE MEDOCARILPTFDAN99027V28J
  • BAL5788CNNCI
  • RO 65-5788CNNCI
  • JNJ30982081CNNCI
DEFINITION
  • A water-soluble prodrug of ceftobiprole, a pyrrolidinone cephalosporin antibiotic, with bactericidal activity. Ceftobiprole binds to and inactivates penicillin-binding proteins (PBPs), enzymes involved in the terminal stages of bacterial cell wall assembly and cell wall reshaping during bacterial growth and division. This agent exhibits a broad spectrum of activity against gram-negative and gram-positive pathogens including methicillin-resistant S. aureus (MRSA), vancomycin-intermediate S. aureus (VISA) and vancomycin-resistant S. aureus (VRSA). Ceftobiprole is refractory to hydrolysis by class A and class C lactamases.NCI
code
  • C70597
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