About: Aminocaproic Acid     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz:8890 associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Aminocaproic Acid
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Aminocaproic Acid
NSC_Code
  • 26154
UMLS_CUI
  • C0000608
CAS_Registry
  • 60-32-2
FDA_UNII_Code
  • U6F3787206
Contributing_Source
  • FDA
Chemical_Formula
  • C6H13NO2
Legacy_Concept_Name
  • Aminocaproic_Acid
CHEBI_ID
  • CHEBI:16586
FULL_SYN
  • 6-Aminohexanoic AcidPTDCP01191
  • Aminocaproic AcidPTNCI
  • AMINOCAPROIC ACIDPTFDAU6F3787206
  • AmicarBRNCI
  • 6-Aminocaproic AcidSNNCI
  • 6-Aminohexanoic AcidSNNCI
  • Epsilon SSYNCI
DEFINITION
  • A synthetic lysine derivative with antifibrinolytic activity. Aminocaproic acid competitively inhibits activation of plasminogen, thereby reducing conversion of plasminogen to plasmin (fibrinolysin), an enzyme that degrades fibrin clots as well as fibrinogen and other plasma proteins including the procoagulant factors V and VIII. Aminocaproic acid competitively reduces the conversion of plasminogen to plasmin by plasminogen activators. It directly inhibits proteolytic activity of plasmin, but higher doses are required than are needed to reduce plasmin formation. Aminocaproic acid is used in the treatment of hemorrhage and prophylactically against hemorrhage, including hyperfibrinolysis-induced hemorrhage and postsurgical hemorrhage.NCI
code
  • C47391
sameAs
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