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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz:8890 associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Lamotrigine
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Organic Chemical
  • Pharmacologic Substance
Preferred_Name
  • Lamotrigine
UMLS_CUI
  • C0678180
CAS_Registry
  • 84057-84-1
Accepted_Therapeutic_Use_For
  • Epilepsy
In_Clinical_Trial_For
  • Chemotherapy-induced peripheral neuropathy
FDA_UNII_Code
  • U3H27498KS
Contributing_Source
  • FDA
ALT_DEFINITION
  • A drug that is used to help control some types of seizures. It is being studied in the prevention of peripheral neuropathy caused by some chemotherapy drugs. It belongs to the family of drugs called anticonvulsants.NCI-GLOSS
PDQ_Open_Trial_Search_ID
  • 328241
PDQ_Closed_Trial_Search_ID
  • 328241
Chemical_Formula
  • C9H7Cl2N5
Legacy_Concept_Name
  • Lamotrigine
CHEBI_ID
  • CHEBI:6367
FULL_SYN
  • LamotriginePTNCI
  • lamotriginePTNCI-GLOSSCDR0000335491
  • LamictalBRNCI
  • LAMOTRIGINEPTFDAU3H27498KS
DEFINITION
  • A synthetic phenyltriazine with antiepileptic and analgesic properties. Lamotrigine enhances the action of gamma-aminobutyric acid, an inhibitory neurotransmitter, which may result in a reduction of pain-related transmission of signals along nerve fibers. This agent may also inhibit voltage-gated sodium channels, suppress glutamate release, and inhibit serotonin reuptake. (NCI04)NCI
DesignNote
  • Clinical Trial--Chemotherapy-induced neuropathy
code
  • C38703
sameAs
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