About: Bicalutamide

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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz:8890 associated with source document(s)

Attributes	Values
rdf:type	Class
rdfs:label	Bicalutamide
rdfs:subClassOf	Anti-Androgen
Concept_In_Subset	FDA Established Names and Unique Ingredient Identifier Codes Terminology
Semantic_Type	Organic Chemical Pharmacologic Substance
Preferred_Name	Bicalutamide
NSC_Code	722665
UMLS_CUI	C0285590
CAS_Registry	90357-06-5
Accepted_Therapeutic_Use_For	Metastatic prostate cancer
In_Clinical_Trial_For	Prostate cancer
FDA_UNII_Code	A0Z3NAU9DP
Contributing_Source	FDA
ALT_DEFINITION	An anticancer drug that belongs to the family of drugs called antiandrogens.NCI-GLOSS
PDQ_Open_Trial_Search_ID	41298
PDQ_Closed_Trial_Search_ID	41298
Chemical_Formula	C18H14F4N2O4S
Legacy_Concept_Name	Bicalutamide
CHEBI_ID	CHEBI:3090
FULL_SYN	(+/-)-N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropanamideSNNCI BicalutamidePTNCI bicalutamidePTNCI-GLOSSCDR0000045354 BicalutamidePTDCP08923 N-[4-Cyano-3-(trifluoromethyl)phenyl]3-3[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methyl-propanamideSNNCI 4-Cyano-3-trifluoromethyl-N-(3-p-fluorophenylsulfonyl-2-hydroxy-2-methylpropionyl)anilineSNNCI 4'-Cyano-alpha,alpha,alpha-trifuloro-3-[(p-fluorophenyl)sulfonyl]-2-methyl-m-lactotoluidideSNNCI CasodexBRNCI CosudexFBNCI ICI 176334CNNCI ICI 176,334CNNCI BICALUTAMIDEPTFDAA0Z3NAU9DP
DEFINITION	A synthetic, nonsteroidal antiandrogen. Bicalutamide competitively binds to cytosolic androgen receptors in target tissues, thereby inhibiting the receptor binding of androgens. This agent does not bind to most mutated forms of androgen receptors. (NCI04)NCI
code	C1599
sameAs	BICALUTAMIDE BICALUTAMIDE
http://linked.open...y/mesh/hasConcept	http://linked.opendata.cz/resource/mesh/concept/M0151653
is someValuesFrom of	nodeID://b645395 nodeID://b650379 nodeID://b650382 nodeID://b650384 nodeID://b650388 nodeID://b650390 nodeID://b650391
is sameAs of	BICALUTAMIDE BICALUTAMIDE BICALUTAMIDE

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