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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz:8890 associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Pimozide
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Pimozide
NSC_Code
  • 170984
UMLS_CUI
  • C0031935
CAS_Registry
  • 2062-78-4
FDA_UNII_Code
  • 1HIZ4DL86F
Contributing_Source
  • FDA
Chemical_Formula
  • C28H29F2N3O
Legacy_Concept_Name
  • Pimozide
CHEBI_ID
  • CHEBI:8212
FULL_SYN
  • OrapBRNCI
  • PIMOZIDEPTFDA1HIZ4DL86F
  • OpiranSYNCI
  • 2H-Benzimidazol-2-one, 1-(1-(4,4-bis(4-fluorophenyl)butyl)-4-piperidinyl)-1,3-dihydro-SNNCI
  • PimozidePTNCI
  • PimozidePTDCP09186
DEFINITION
  • A diphenylbutylpiperidine derivative and a dopamine antagonist with antipsychotic property. Pimozide selectively inhibits type 2 dopaminergic receptors in the central nervous system (CNS), thereby decreasing dopamine neurotransmission and reducing the occurrence of motor and vocal tics and delusions of parasitosis. In addition, this agent antagonizes alpha-adrenergic and 5-HT2 receptors.NCI
code
  • C47672
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