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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz:8890 associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Anagrelide Hydrochloride
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Organic Chemical
  • Pharmacologic Substance
Preferred_Name
  • Anagrelide Hydrochloride
NSC_Code
  • 724577
UMLS_CUI
  • C0771907
CAS_Registry
  • 58579-51-4
FDA_UNII_Code
  • VNS4435G39
Contributing_Source
  • FDA
Chemical_Formula
  • C10H7Cl2N3O.ClH
Legacy_Concept_Name
  • Anagrelide_Hydrochloride
CHEBI_ID
  • CHEBI:55345
FULL_SYN
  • Anagrelide HydrochloridePTNCI
  • ANAGRELIDE HYDROCHLORIDEPTFDAVNS4435G39
  • AgrylinBRNCI
DEFINITION
  • The hydrochloride salt of a synthetic quinazoline derivative, Anagrelide Hydrochloride reduces platelet production through a decrease in megakaryocyte maturation. Anagrelide inhibits cyclic AMP phosphodiesterase, as well as ADP- and collagen-induced platelet aggregation. At therapeutic doses, it does not influence white cell counts or coagulation parameters. Anagrelide is used for treatment of essential thrombocythemia to reduce elevated platelet counts and the risk of thrombosis. (NCI04)NCI
code
  • C28826
is Has_Salt_Form of
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