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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz:8890 associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Anagrelide
rdfs:subClassOf
Has_Salt_Form
Concept_In_Subset
Semantic_Type
  • Organic Chemical
  • Pharmacologic Substance
Preferred_Name
  • Anagrelide
UMLS_CUI
  • C0051809
CAS_Registry
  • 68475-42-3
FDA_UNII_Code
  • K9X45X0051
Contributing_Source
  • FDA
ALT_DEFINITION
  • A drug that is used to decrease the number of platelets in the blood in order to prevent blood clotting.NCI-GLOSS
Chemical_Formula
  • C10H7Cl2N3O
Legacy_Concept_Name
  • Anagrelide
CHEBI_ID
  • CHEBI:142290
FULL_SYN
  • anagrelidePTNCI-GLOSSCDR0000302451
  • ANAGRELIDEPTFDAK9X45X0051
  • AnagrelidePTNCI
DEFINITION
  • A synthetic quinazoline derivative, Anagrelide reduces platelet production through a decrease in megakaryocyte maturation. Anagrelide inhibits cyclic AMP phosphodiesterase, as well as ADP- and collagen-induced platelet aggregation. At therapeutic doses, it does not influence white cell counts or coagulation parameters. Anagrelide is used for treatment of essential thrombocythemia to reduce elevated platelet counts and the risk of thrombosis. (NCI04)NCI
code
  • C28825
is Has_Free_Acid_Or_Base_Form of
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