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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz:8890 associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Nafcillin Sodium Anhydrous
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Nafcillin Sodium Anhydrous
UMLS_CUI
  • C2698426
CAS_Registry
  • 985-16-0
FDA_UNII_Code
  • SY07234TTS
Contributing_Source
  • FDA
Chemical_Formula
  • C21H21N2O5S.Na
Legacy_Concept_Name
  • Nafcillin_Sodium_Anhydrous
CHEBI_ID
  • CHEBI:7448
FULL_SYN
  • Nafcillin Sodium AnhydrousPTNCI
  • NAFCILLIN SODIUM ANHYDROUSPTFDASY07234TTS
DEFINITION
  • The anhydrous form of the sodium salt of nafcillin, a narrow-spectrum beta-lactamase-resistant penicillin with antibacterial activity. Nafcillin binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This interrupts bacterial cell wall synthesis and results in the weakening of the bacterial cell wall, eventually causing cell lysis.NCI
code
  • C76224
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