About: Kanamycin Sulfate     Goto   Sponge   Distinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz:8890 associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Kanamycin Sulfate
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Kanamycin Sulfate
UMLS_CUI
  • C0700540
CAS_Registry
  • 133-92-6
  • 25389-94-0
FDA_UNII_Code
  • OW1N4G4R9W
Contributing_Source
  • FDA
PDQ_Open_Trial_Search_ID
  • 564417
PDQ_Closed_Trial_Search_ID
  • 564417
Legacy_Concept_Name
  • Kanamycin_Sulfate
CHEBI_ID
  • CHEBI:6109
FULL_SYN
  • Kanamycin SulfatePTNCI
  • KANAMYCIN SULFATEPTFDAOW1N4G4R9W
DEFINITION
  • The sulfate salt of kanamycin, a naturally occurring aminoglycoside antibiotic with antimicrobial property. Derived from Streptomyces kanamyceticus, kanamycin is an antibiotic complex consisting of three components: kanamycin A, the major component (also usually designated as kanamycin), and kanamycins B and C, the minor components. This agent irreversibly binds to the bacterial 30S ribosomal subunit. Specifically, this antibiotic is lodged between 16S rRNA and S12 protein within the 30S subunit. This leads to interference with translational initiation complex, misreading of mRNA, thereby hampering protein synthesis and resulting in bactericidal effect. Aminoglycosides are mostly ineffective against anaerobic bacteria, fungi and viruses.NCI
code
  • C65998
sameAs
http://linked.open...y/mesh/hasConcept
is Has_Salt_Form of
is sameAs of
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