About: Carbidopa Anhydrous     Goto   Sponge   Distinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz:8890 associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Carbidopa Anhydrous
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Carbidopa Anhydrous
UMLS_CUI
  • C1881339
CAS_Registry
  • 28860-95-9
FDA_UNII_Code
  • KR87B45RGH
Contributing_Source
  • FDA
Chemical_Formula
  • C10H14N2O4
Legacy_Concept_Name
  • L-Carbidopa_Anhydrous
CHEBI_ID
  • CHEBI:39585
FULL_SYN
  • Benzenepropanoic Acid, alpha-hydrazino-3,4-Dihydroxy-alpha-methyl-, (S)-SNNCI
  • Carbidopa AnhydrousPTNCI
  • CARBIDOPA ANHYDROUSPTFDAKR87B45RGH
  • L-Carbidopa AnhydrousSYNCI
DEFINITION
  • The anhydrous, levorotatory isomer of a synthetic hydrazine derivative of the neurotransmitter dopamine. Carbidopa, a peripheral dopa decarboxylase inhibitor, is used as an adjunct with levodopa to prevent levodopa degradation to dopamine in extracerebral tissue, thereby decreasing the peripheral side effects of levodopa. Carbidopa does not penetrate the blood brain barrier; therefore, it does not interfere with the central nervous system (CNS) metabolism of levodopa to the active neurotransmitter dopamine which, in high concentrations in the brain, has anti-parkinsonian effects.NCI
code
  • C61803
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