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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz:8890 associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Fosfomycin
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Fosfomycin
UMLS_CUI
  • C0016610
CAS_Registry
  • 23155-02-4
FDA_UNII_Code
  • 2N81MY12TE
Contributing_Source
  • FDA
Chemical_Formula
  • C3H7O4P
Legacy_Concept_Name
  • Fosfomycin
CHEBI_ID
  • CHEBI:28915
FULL_SYN
  • FOSFOMYCINPTFDA2N81MY12TE
  • FosfomycinPTNCI
DEFINITION
  • A phosphoenolpyruvate analogue and a synthetic broad-spectrum antibiotic with antimicrobial and bactericidal properties. Fosfomycin binds to and inactivates the enzyme enolpyruvate transferase. This leads to an irreversible blockage of the condensation of uridine diphosphate-N-acetylglucosamine with p-enolpyruvate, which is one of the first steps of bacterial cell wall synthesis, thereby eventually causing cell lysis and bacterial cell death.NCI
code
  • C61772
sameAs
http://linked.open...y/mesh/hasConcept
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