About: Potassium-Sparing Diuretic

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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz:8890 associated with source document(s)

Attributes	Values
rdf:type	Class
rdfs:label	Potassium-Sparing Diuretic
rdfs:subClassOf	DIURETICS
Semantic_Type	Chemical Viewed Functionally
Preferred_Name	Potassium-Sparing Diuretic
UMLS_CUI	C0304490
Legacy_Concept_Name	Potassium-Sparing_Diuretic
FULL_SYN	Potassium-Sparing DiureticPTNCI
DEFINITION	Any diuretic agent that produces diuresis without increasing potassium excretion. Potassium sparing diuretics are generally either aldosterone antagonists and thus prevent the aldosterone-mediated promotion of sodium and water retention, or are epithelial sodium channel blockers and prevent the exchange of potassium for sodium in the distal convoluted tubule. These agents cause diuresis without increasing potassium secretion and thus do not cause hypokalemia.NCI
code	C49186
http://linked.open...y/mesh/hasConcept	http://linked.opendata.cz/resource/mesh/concept/M0471880
is rdfs:subClassOf of	TRIAMTERENE Mespirenone Amiloride Hydrochloride AMILORIDE Azolimine Canrenone SPIRONOLACTONE Prorenoate Prorenoate Potassium

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