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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz:8890 associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Epigenetic Silencing
rdfs:subClassOf
Semantic_Type
  • Genetic Function
Preferred_Name
  • Epigenetic Silencing
UMLS_CUI
  • C1707931
Legacy_Concept_Name
  • Epigenetic_Silencing
FULL_SYN
  • Epigenetic SilencingPTNCI
DEFINITION
  • This process is initiated by the formation of heterochromatin which ultimately leads to transcriptional inactivation or silencing. Once formed, heterochromatin can be inherited through many cell divisions, including meiosis. Inappropriate gain of heterochromatin structure, such as the inactivation of tumor suppressor genes by DNA hyper-methylation at their promoter regions, can be directly linked to carcinogenesis.NCI
code
  • C48186
is someValuesFrom of
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