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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz:8890 associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Methsuximide
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Methsuximide
UMLS_CUI
  • C0109002
CAS_Registry
  • 77-41-8
FDA_UNII_Code
  • 0G76K8X6C0
Contributing_Source
  • FDA
Chemical_Formula
  • C12H13NO2
Legacy_Concept_Name
  • Methsuximide
FULL_SYN
  • METHSUXIMIDEPTFDA0G76K8X6C0
  • MethsuximidePTNCI
  • Succinimide, N,2-dimethyl-2-phenyl-SNNCI
  • CelontinBRNCI
  • 1,3-Dimethyl-3-phenyl-2,5-dioxopyrrolidineSNNCI
DEFINITION
  • A succinimide with anticonvulsant properties. Although the exact mechanism of action of methsuximide is unclear, it is thought to increase the seizure threshold and suppress the paroxysmal three-cycle-per-second spike-and-wave pattern seen with absence (petit mal) seizures. The frequency of attacks is reduced by depression of nerve transmission in the motor cortex and elevation of the threshold of the CNS to convulsive stimuli, probably due to direct modification of membrane function in excitable cells and/or alteration of chemically mediated neurotransmission.NCI
code
  • C47613
sameAs
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