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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz:8890 associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Clofazimine
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Clofazimine
NSC_Code
  • 141046
UMLS_CUI
  • C0008996
CAS_Registry
  • 2030-63-9
FDA_UNII_Code
  • D959AE5USF
Contributing_Source
  • FDA
Legacy_Concept_Name
  • Clofazimine
CHEBI_ID
  • CHEBI:3749
FULL_SYN
  • ClofaziminePTNCI
  • 3-(p-Chloranilino)-10-(p-chlorophenyl)-2,10-dihydro-2-(isopropylimino)-phenazineSNNCI
  • LampreneBRNCI
  • CLOFAZIMINEPTFDAD959AE5USF
  • 2-Phenazinamine, 3,5-dihydro-N,5-bis(4-chlorophenyl)-3-((1-methylethyl)imino)-SNNCI
DEFINITION
  • A phenazine dye with anti-mycobacterial and anti-inflammatory activities. The exact mechanism through which clofazimine exerts its effect is unknown. However, it binds preferentially to mycobacterial DNA, thereby inhibiting DNA replication and cell growth. Clofazimine has a slow bactericidal effect on Mycobacterium leprae and is active against various other Mycobacteria.NCI
code
  • C47456
sameAs
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