About: Xanthine Dehydrogenase     Goto   Sponge   Distinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz:8890 associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Xanthine Dehydrogenase
rdfs:subClassOf
OMIM_Number
  • 607633
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Enzyme
Preferred_Name
  • Xanthine Dehydrogenase
UMLS_CUI
  • C0043316
Legacy_Concept_Name
  • Xanthine_Dehydrogenase
FULL_SYN
  • EC 1.1.1.204SYNCI
  • Xanthine DehydrogenasePTNCI
  • Xanthine OxidoreductaseSYNCI
  • XDHSYNCI
  • Xanthine OxidaseSYNCI
  • EC 1.1.3.22SYNCI
Swiss_Prot
  • P47989
DEFINITION
  • A homodimer, belongs to the family of molybdenum-containing hydroxylases involved in the oxidative metabolism of purines. Xanthine dehydrogenase can be converted to xanthine oxidase by reversible sulfhydryl oxidation or by irreversible proteolytic modification. Xanthine oxidase (EC 1.1.3.22), a unimolecular, multicomponent electron transport system (with cofactors), catalyzes the oxidation of xanthine to uric acid. Xanthine dehydrogenase is the mian form exists in liver in vivo. Defects in xanthine dehydrogenase cause xanthinuria, may contribute to adult respiratory stress syndrome, and may potentiate influenza infection through an oxygen metabolite-dependent mechanism. (NCI)NCI
code
  • C39587
sameAs
http://linked.open...y/mesh/hasConcept
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