About: Immunohistochemistry Staining Method     Goto   Sponge   Distinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz:8890 associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Immunohistochemistry Staining Method
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Laboratory Procedure
Display_Name
  • Immunohistochemistry Staining Method
Preferred_Name
  • Immunohistochemistry Staining Method
UMLS_CUI
  • C0021044
Contributing_Source
  • CDISC
ALT_DEFINITION
  • A technique used to identify specific molecules in different kinds of tissue. The tissue is treated with antibodies that bind the specific molecule. These are made visible under a microscope by using a color reaction, a radioisotope, colloidal gold, or a fluorescent dye. Immunohistochemistry is used to help diagnose diseases, such as cancer, and to detect the presence of microorganisms. It is also used in basic research to understand how cells grow and differentiate (become more specialized).NCI-GLOSS
  • Immunohistochemical staining techniques allow for the visualization of antigens via the sequential application of a specific antibody to the antigen (primary antibody), a secondary antibody to the primary antibody and an enzyme complex with a chromogenic substrate. The enzymatic activation of the chromogen results in a visible reaction product at the antigen site. The specimen may then be counterstained and coverslipped. Results are interpreted using a light microscope and aid in the differential diagnosis of pathophysiological processes, which may or may not be associated with a particular antigen.CDISC
Legacy_Concept_Name
  • Immunohistochemistry_Staining_Method
FULL_SYN
  • ImmunohistochemistrySYCTRM
  • ImmunohistochemistrySYCDISC
  • Cell/Tissue, ImmunohistochemistrySYNCI
  • IHCABNCI
  • Immunohistochemistry Staining MethodPTNCI
  • IHCSYCTRM
  • IHCPTCDISC
  • Immunohistochemistry Staining MethodDNCTRM
  • immunohistochemistryPTNCI-GLOSSCDR0000653117
  • Immunohistochemistry Staining MethodSYNCITCGA
  • ImmunohistochemistrySYNCI
DEFINITION
  • Immunohistochemical staining techniques allow for the visualization of antigens via the sequential application of a specific antibody to the antigen (primary antibody), a secondary antibody to the primary antibody and an enzyme complex with a chromogenic substrate. The enzymatic activation of the chromogen results in a visible reaction product at the antigen site. The specimen may then be counterstained and coverslipped. Results are interpreted using a light microscope and aid in the differential diagnosis of pathophysiological processes, which may or may not be associated with a particular antigen.NCI
code
  • C23020
http://linked.open...y/mesh/hasConcept
is rdfs:subClassOf of
Faceted Search & Find service v1.16.121 as of Mar 31 2025


Alternative Linked Data Documents: ODE     Content Formats:   [cxml] [csv]     RDF   [text] [turtle] [ld+json] [rdf+json] [rdf+xml]     ODATA   [atom+xml] [odata+json]     Microdata   [microdata+json] [html]    About   
This material is Open Knowledge   W3C Semantic Web Technology [RDF Data]
OpenLink Virtuoso version 07.20.3240 as of Mar 31 2025, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 13 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2025 OpenLink Software