About: Interleukin-1-Alpha     Goto   Sponge   Distinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz:8890 associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Interleukin-1-Alpha
equivalentClass
OMIM_Number
  • 147760
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Biologically Active Substance
  • Immunologic Factor
Preferred_Name
  • Interleukin-1-Alpha
UMLS_CUI
  • C0600251
ALT_DEFINITION
  • One of a group of related proteins made by leukocytes (white blood cells) and other cells in the body. IL-1-alpha, one form of IL-1, is made mainly by one type of white blood cell, the macrophage, and helps another type of white blood cell, the lymphocyte, fight infections. It also helps leukocytes pass through blood vessel walls to sites of infection and causes fever by affecting areas of the brain that control body temperature. The other form of IL-1, IL-1-beta, acts the same as IL-1-alpha. IL-1-alpha made in the laboratory is used as a biological response modifier to boost the immune system in cancer therapy. IL-1-alpha is a type of cytokine.NCI-GLOSS
Legacy_Concept_Name
  • Interleukin-1-Alpha
FULL_SYN
  • Preinterleukin 1 AlphaSYNCI
  • IL1A ProteinSYNCI
  • interleukin-1-alphaPTNCI-GLOSSCDR0000044044
  • IL1SYNCI
  • Hematopoietin-1SYNCI
  • IL1ASYNCI
  • IL-1ASYNCI
  • IL1F1SYNCI
  • IL-1-aSYNCI
  • Interleukin 1-AlphaSYNCI
  • Interleukin-1-AlphaPTNCI
  • Interleukin 1, AlphaSYNCI
  • IL1-AlphaSYNCI
  • IL-1alphaSYNCI
  • IL-1-alphaPTNCI-GLOSSCDR0000522475
Swiss_Prot
  • P01583
DEFINITION
  • Human interleukin-1 protein (271 aa, 31 kD precursor) is encoded by the human interleukin-1 (IL1) gene. This soluble protein is produced primarily by monocytes and macrophages. It activates and potentiates T-lymphocyte responses to mitogens or antigens. This protein is also capable of replacing macrophage requirements for T-cell activationNCI
code
  • C20521
sameAs
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